Outreach

21. L. Koch, S. Andreotti, M. Schubert, E. Liebhart, AM. Zürbig, J. Gatzki, BF. Hempel, L. Kolhoff, B. Feldmeyer, M. Herzberg, VIC. Rebhahn, NN. Win, AC. LeBoeuf, M. Meleshin, F. Herrmann, C. Schwieger, H. Brötz-Oesterhelt, A. Sinz, M. Schutkowski, THJ. Niedermeyer┼, S. Tragust┼ “Beyond formic acid: Peptides in carpenter ant venoms aid in disease protection” Sci Adv 2026, 12; doi: 10.1126/sciadv.aed4078.

20. M. Grzeski, P. M. Jensen, BF. Hempel, H. Thiele, J. Lellmann, S. Schallenberg, V. Budach, U. Keilholz, I. Tinhofer, O. Klein┼ “Integrating MALDI-MSI-Based Spatial Proteomics and Machine Learning to Predict Chemoradiotherapy Outcomes in Head and Neck Cancer” Int J Mol Sci 2025; doi: 10.3390/ijms26189084.

19. ZD. Musimbi, A. Laubschat, L. Oser1, RM. Mugo, BF. Hempel, P. Höfler, J. Schlosser-Brandenburg, A. Midha, S. Rausch, S. Hartmann┼ “Larval ascariasis elicits a prominent IgA and IgG1/2 antibody response to adult Ascaris excretory/secretory antigens in pigs” Front Immunol 2025; doi: 10.3389/fimmu.2025.1606128.

18. M. Lakušić, F. Martinez-Freiria, M. Anđelković, BF. Hempel┼ “Beyond sexual maturity: Importance of dietary changes in venom variation in Vipera ammodytes” Toxicon 2025; doi: 10.1016/j.toxicon.2025.108291.

17. AK. Langenhagen, AFH. Haake, VM. Jovanovic, S. Andreotti, M. Hummel, BF. Hempel, AD. Gruber┼ “Immuno-oncologic profling by stage-dependent transcriptome and proteome analyses of spontaneously regressing canine cutaneous histiocytoma” PeerJ 2024; doi: 10.7717/peerj.18444.

16. G. Zancolli*,┼, BM. von Reumont*, G. Anderluh, F. Caliskan, ML. Chiusano, J. Fröhlich, E. Hapeshi, BF. Hempel, MP. Ikonomopoulou, F. Jungo, P. Marchot, TM. de Farias, MV. Modica, Y. Moran, A. Nalbantsoy, J. Prochazka, A. Tarallo, F. Tonello, R. Vitorino, ML. Zammit, A. Antunes┼ “Web of venom: exploration 1 of big data resources in animal toxin research” GigaScience 2024, 13; doi: 10.1093/gigascience/giae054.

15. EL. Pinheiro-Junior*, E. Alirahimi*, S. Peigneur, J. Isensee, S. Schiffmann, P. Erkoc, R. Fürst, A. Vilcinskas, T. Sennoner, I. Koludarov, BF. Hempel, J. Tytgat, T. Hucho , BM. von Reumont┼ “Variants of diversely evolved xibalbins from remipede venom inhibit potassium channels and activate PKA-II and Erk1/2 signalling” BMC Biol 2024; doi: 10.1186/s12915-024-01955-5.

14. BF. Hempel┼, M. Damm, D. Petras, TD. Kazandjian, NR. Casewell, CA. Szentiks, G. Fritsch, G. Nebrich, NR. Casewell, O. Klein, RD. Süssmuth┼ “Spatial Venomics – Cobra Venom System Reveals Spatial distinction of Snake Toxins by Mass Spectrometry Imaging” J Prot Res 2023; doi: 10.1021/acs.jproteome.2c00424.

13. BM. von Reumont┼, G. Anderluh, A. Antunes, N. Ayvazyan, D. Beis, F. Caliskan, A. Crnković, M. Damm, S. Dutertre, L. Ellgaard, … , BF. Hempel, … , G. Zancolli “Modern venomics – Current insights, novel methods and future perspectives in biological and applied animal venom research” GigaScience 2022, 11; doi: 10.1093/gigascience/giac048.

12. JJ. Calvete┼, D. Pla, J. Els, S. Carranza, M. Damm, BF. Hempel, EBO. John, D. Petras, P. Heiss, A. Nalbantsoy, B. Göçmen, RD. Süssmuth, F. Calderón-Celis, AJ. Nosti, JR. Encinar “Combined Molecular and Elemental Mass Spectrometry Approaches for Absolute Quantification of Proteomes: Application to the Venomics Characterization of the Two Species of Desert Black Cobras, Walterinnesia aegyptia and Walterinnesia morgani” J Prot Res 2021; doi: 10.1021/acs.jproteome.1c00608.

11. N. Rügen, T. P. Jenkins, N. Wielsch, H. Vogel, BF. Hempel, RD. Süssmuth, S. Ainsworth, A. Cabezas-Cruz, A. Vilcinskas, M. Tonk┼ “Hexapod Assassins’ Potion: Venom Composition and Bioactivity from the Eurasian Assassin Bug Rhynocoris iracundus” Biomedicines 2021, 9(7), 819; doi: 10.3390/biomedicines9070819.

10. M. Damm, BF. Hempel, RD. Süssmuth┼ “Old World Vipers — A Review about Snake Venom Proteomics of Viperinae and Their Variations” Toxins 2021, 13(6), 427; doi: 10.3390/toxins13060427.

9. M. A Schorn, S. Verhoeven, L. Ridder, F. Huber, D. D. Acharya, A. A Aksenov, G. Aleti, J. A. Moghaddam, A. T. Aron, S. Aziz, … , BF. Hempel, … , P. C. Dorrestein┼, M. H. Medema┼, J. JJ. van der Hooft┼ “ A community resource for paired genomic and metabolomic data mining” Nat Chem Bio 2021, 17, 363-368, doi: 10.1038/s41589-020-00724-z.

8. BF. Hempel*, M. Damm*, Mrinalini*, B. Göçmen, M. Karisc, A. Nalbantsoy, RM. Kinib, RD. Süssmuth┼ “Extended Snake Venomics by Top-Down In-Source Decay: Investigating the Newly Discovered Anatolian Meadow Viper Subspecies, Vipera anatolica senliki” J Prot Res 2020, 19(4), 1731-1749; doi: 10.1021/acs.jproteome.9b00869.

7. NR. Casewell┼, D. Petras, DC. Card, V. Suranse, AM. Mychajliw, D. Richards, I. Koludarov, LO. Albulescu, J. Slagboom, BF. Hempel, NM. Ngum, RJ. Kennerley, JL. Brocca, G. Whiteley, RA. Harrison, FMS. Bolton, J. Debono, FJ. Vonk, J. Alföldi, J. Johnson, E. Karlsson, K. Lindblad-Toh, I. Mellor, RD. Süssmuth, BG. Fry, S. Kuruppu, WC. Hodgson, J. Kool, TA. Castoe, I. Barnes, K. Sunagar, EAB. Undheim and ST. Turvey “Solenodon genome reveals convergent evolution of venom in eulipotyphlan mammals.” PNAS 2019; doi: 10.1073/pnas.1906117116.

6. CS. Ozverel*, M. Damm*, BF. Hempel┼, B. Göçmenc, R. Sroka, RD. Süssmuth, A. Nalbantsoy┼ “Investigating the cytotoxic effects of the venom proteome of two species of the Viperidae family (Cerastes cerastes and Cryptelytrops purpureomaculatus) from various habitats.” Comp Biochem Physiol C 2019; doi: 10.1016/j.cbpc.2019.02.013.

5. D. Petras*,┼, BF. Hempel*, B. Göçmen, M. Karis, G. Whiteley, SC. Wagstaff, P. Heiss, NR. Casewell, A. Nalbantsoy┼, RD. Süssmuth┼ “Intact protein mass spectrometry reveals intraspecies variations in venom composition of a local population of Vipera kaznakovi in Northeastern Turkey.” J Prot 2019, 199, 31-50; doi: 10.1016/j.jprot.2019.02.004.

4. M. Damm*, BF. Hempel*, A. Nalbantsoy, RD. Süssmuth┼ “Comprehensive Snake Venomics of the Okinawa Habu Pit Viper, Protobothrops flavoviridis, by Complementary Mass Spectrometry-Guided Approaches.” Molecules 2018, 23(8), 1893; doi: 10.3390/molecules23081893.

3. BF. Hempel, M. Damm, B. Göçmen, M. Karis, MA. Oguz, A. Nalbantsoy, RD. Süssmuth┼ “Comparative Venomics of the Vipera ammodytes transcaucasiana and Vipera ammodytes montandoni from Turkey Provides Insights into Kinship.” Toxins 2018; 10(1), 23; doi:10.3390/toxins10010023.

2. A. Nalbantsoy*, BF. Hempel*, D. Petras, P. Heiss, B. Göçmen, N. Iğci, MZ. Yildiz, RD. Süssmuth┼ “Combined venom profiling and cytotoxicity screening of the Radde's mountain viper (Montivipera raddei) and Mount Bulgar Viper (Montivipera bulgardaghica) with potent cytotoxicity against human A549 lung carcinoma cells.” Toxicon 2017; 

doi: 10.1016/j.toxicon.2017.06.008.

1. D. Petras, D. Kerwat, A. Pesic, BF. Hempel, L. von Eckardstein, S. Semsary, J. Arasté, M. Marguerettaz, M. Royer, S. Cociancich, RD. Süssmuth┼ “The O-Carbamoyl-Transferase Alb15 Is Responsible for the Modification of Albicidin.” ACS Chem Biol 2016, 11(5), 1198-1204; doi: 10.1021/acschembio.5b01001.

Currently being processed

Decoding Venom Systems by Mass Spectrometry Imaging

Oral presentation (selected)

08-10th April 2026, 1st EuroMass Imaging, Esch-sur-Alzette, Luxembourg.

Decoding Venom Systems by Mass Spectrometry Imaging

Poster presentation (selected)

04-07th March 2025, DGMS Annual Conference, Göttingen, Germany. 

Fanatastic Venoms…and where to find them – Mass spectrometry imaging of venom systems to decipher evolutionary biology of toxins for spatial differentiation

Oral presentation (invited)

6th November 2024, Venom Day, Bangor, Wales UK. 

Revealing Venom Secrets: Advances in Mass Spectrometry Imaging

Oral presentation (selected)

23-25th August 2024, 2nd International EUVEN Congress, Naples, Italy.

Decoding Venom Systems to Trace Adaption via Mass Spectrometry Imaging

Oral presentation (invited)

12-15th August 2024, Gordon Researc hConference, Portland, Maine (USA).

Fanatastic Venoms…and where to find them – Mass spectrometry imaging of venom systems to decipher evolutionary biology of toxins for spatial differentiation

Oral presentation (selected)

24-28th June 2024, 2nd International EUVEN Congress, Madrid, Spain.

Fanatastic Venoms…and where to find them – Mass spectrometry imaging of venom systems to decipher evolutionary biology of toxins for spatial differentiation

Oral presentation (invited)

12th December 2023, CBIO, Porto, Portugal. 

Spatial Venomics – Cobra Venom System Reveals Spatial Differentiation of Snake Toxins by Mass Spectrometry Imaging

Oral presentation (invited)

6th December 2022, St. Nicholas Symposium, Charite, Berlin, Germany,

Spatial venomics: Toxin production and functional biology of glycerid toxins by mass spectrometry imaging

Oral presentation (selected)

14th-16th September 2021, 1st International Congress European Venom Network, online.

Spatial Mapping of Venom Toxins by Mass Spectrometry Imaging

Poster presentation (selected)

19th-22th October 2020, 19th Human Proteome Organization World Congress, online.